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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd50a7871c61480f9376271f9299e23d48d341facdb5f200b30868b54b29f476' 
  AND token = 'xrB3AP6eG2c5Ia5RDyGqLWLFPnYXhiIeDrHkKjaXihc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}