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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31ad41cc2e1e688b99a153fbfba587f11b59c6bf222dc4e157c829fddcdcc602' 
  AND token = 'FZsMW2Tt/eLe6eEQJPQCtp1h5ohx5aDBbvzKQICZY3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}