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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab5922fc7f23cb4dad64a7a5fdeae59ada755ffe79a043c982f9cd353370ea8a' 
  AND token = 's8haOVPp+S/NdEE/c1Fj/dtfW0gc4nPxLQBMoxDBKQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}