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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '220bb31d8089fd44b8a8e8166affe5510a2e6e82438bd4fd7ed2b659921a7302' 
  AND token = '8iXlZrJxtoro7gKCgbiLap3QINDwT9YRQmTTWlRTWaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}