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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a20ac74481c3247b661a1aff69a6bc293599aa26827ce4c1c7edbf435a1ecbf' 
  AND token = 'ttSGUvMMHTOwtVkcd3yKi30B75+q6NX81+nALs1qINQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}