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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35e16def049db52dd6e298545213d99d2030aeddccc469f9b0551aaaa084f39e' 
  AND token = 'Vlf50Bzg04l/xUQAmE+mH48j6cqXoecd1Cg7qovQm4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}