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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '016b274be6eaa8be491aef211ad04a16af99bb70cf646b70cfaf34be9c7c2220' 
  AND token = '2XHvCGqn9hiSYPI1uPi+lZ7/g2w15LL4ee14oKI3A+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}