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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7745d16fc631e80549d5b5998268833f6c8cba1fbe77952cf5f5e8c520de5cf0' 
  AND token = 'vorRDA7prY19HM8zChYDGy/9fox+WnlMrLzoIOqVzYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}