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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a88f392f508c4bda28ac07ec45216e63ffd4dc24c07fc9ebc1993938a429fbf' 
  AND token = '8DLfU4g2IK8TZub2ruf4QkvNnd8NfI0zdArBzfTk2PQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}