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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cad578c0b7069c39f0c936e3653b593fd194d9005af977976b25e656da38a7d9' 
  AND token = 'ZIrKWoPGRiMyikjfjH04JSdDZ5cH+43MuxdfZaXoUj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}