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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47ef9f8db10c226d247db78c3a79738c5a0fdadb9e20a00a32f9d4feee8c0071' 
  AND token = 'Or4mcA/+wQcBxLq2+Nngvn989QVmBPXD3E8F2mRr2Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}