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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be01d7c193b617b9bddde3dd60ab6937f17dce9aea454be2309a31a5e46a4ba5' 
  AND token = 'BOhioLryJwUJx+wJzeJ1hEK4YQjL3O/ao/NBvrYBHfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}