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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427741e09bd9f8fa70b92599e49ae4d4e769d5078ba7de8b052b24da2a56d1b6' 
  AND token = 'qhQLfONrN4t5xDwNZ8cU0fLUYRTqqR+NJ5GOmLasrjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}