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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a395a77bda57fd955af210020d2e6be14076a5fdfb16a4e1a48fecefb2be2c4a' 
  AND token = 'FR00uzDomiwuftGF7rVub3zn5zXI9hKxp8b4S5opVok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}