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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd85fd751cab8f00d134fc5af00d06fc0c66544d1778511e43988c1288ebd3343' 
  AND token = 'TdAO8pNxfrVb6epKjFJ5rUQh1M6p4gcyZgLOX7t7DlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}