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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2288ed20c51dc21148982fb5c4d04cd21106a07e8478942f03e48a9428c49ba1' 
  AND token = 'm/jFWXqW+SPoK/VHldz8Hma7llFLMICKV+lfmVL3Ai0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}