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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd67b64fb2758e440dfb7c02f4a070c3b9f1ad0f49d4e53e3b9db70d227e8ed9' 
  AND token = 'kzu+jb28dn6/f2PeMGwtXjf6mSH7kmytTA28bMyFTe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}