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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5f9379d98520832755a42c3faa6fdd240e0c5b0ac2bdbb77cd87bf610f74df6' 
  AND token = '5+iTFdNYe1yC0igrgNi3jh4lq25xvz+I9xQdxQdG1/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}