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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34e070cf60be9063c579e2b446cfed76a3bf74dc2570387677f6cb0e5a83fcd1' 
  AND token = 'w7JZlM3gBr6rkOzKEZ2fkDX1Xf/S9inmwSjTLpiwrU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}