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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e72597370aa427327f443a9876a5a9ed360348aa21b91e38165ad8eeebd9706' 
  AND token = '00QLuMbFTDRJc9FgxBL4V8zmEDQ4I8Qncv0agyBdods=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}