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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '279905fca12876e77024ddf9c65c54fef8b0d31f4f94738bf3fbbb0e3ed41e38' 
  AND token = '7aj9Vvqur2/Y9/IW8TKwO6rinSAV7DwcDOWjD1aKfmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}