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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8cda9d78347537a7f004b5f0ae840c79f46825eaeb48d24c5fe91c89f8c5864' 
  AND token = 'dxb5mxJK/KM3vslzdOM/6PJzVqIKKeU6Qf8SrI59wmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}