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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14dd0669683f5c43658e5fddba92cfe7bd74ca1ab28fada44f6b538daabc244d' 
  AND token = 'Td73cijGDn/aTAEF7HxWb4B6Uo30W4hOnx1EekwZANk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}