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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeb13a58ebd8e78fa86e637e3fbc587c9ef34f20a1fe2a807a171df7374992a4' 
  AND token = 'Zfmkdv1EaGL777cJDGXHrw1Z2dCKZqIrAHs4j4R+3TE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}