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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d10f71b3a08d66a266520c1090db5a479f367e2e95476ca46579919dc8678c1' 
  AND token = 'TRcehsq1CdvJobN180e+TLE6xAAw/OMbPXCI/rPNrvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}