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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bb45d75c61524befcde0f724e549f41d80a8d45687ae78b010466fdbd9325a4' 
  AND token = 'Zw2G39o8n3/svvRJ4J+L6bVka92uo9Nb78KsEUJHohY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}