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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c9d0b946ebaf34d896998dace95d4af1553c0799b0ca3528b47667e99c42b60' 
  AND token = 'lR+QVQ8RqVkGvIOetxm0ZbqQ6e2XeWX7F07aqTHAqNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}