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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2cdcfc75d90cea384820ed444b4b14b21ae4ae9520b21a0849210cd8d17fe2b' 
  AND token = 'OP0daAPDuNVFPQQzOk3TEOQBsDbhjqP6oJzSvW4Hclo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}