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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e665d9c8b15702a5c6fc6636beb9bbbcbb325572fea0501d1e3f481ab0e92423' 
  AND token = 'Wk37fJuMnOoS+d8q5VxrE7IbCtQ84X4qK4YCnqXxeQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}