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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ff75234e97404d8b559377247778a439368f3b8f36c955e4b027544ed74313e' 
  AND token = '5ZCp4WreJblpE5S1nnohv9XcvayirK58SO0WuQojiZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}