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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88e0c3fe30906a7f5bc39dd99142b9b00f8ce875f5c76273343ae464e2a9ccf6' 
  AND token = 'R3opEvQ5APEaODXZj8ro1RTzTVMIwhh5OyQfEjOm1/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}