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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33dc0f23d0cde587a1e003f7a0451a4d624db43251ae7a7c9666b5ba74833aed' 
  AND token = 'EmcPtI+GE7FPDZ7my42R7yfnPWFurvdk398YmulBHeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}