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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3541aed240db081e72687cca3fce592794f0916991e63ff5d8273c856cac5bf' 
  AND token = '29DMsOUiYudYfUsiclD7vdB56t8K22V11udeY/Gw+I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}