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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e949986d73c4bc7f3b782fe42d248c9bb50fb60cf4080ae2e41e1f61a3c240e7' 
  AND token = 'mTEegZzZoMpEl+/b3t6I1AyrcTAB02w7fhdj+AKatHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}