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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d152ccf164ff89eb6b05248f85f0ff720813b6b7fe4a0d0682dcdf72028f72b' 
  AND token = 'TIAtfv+BWbvFgXDdGF+h0nBxK02wP3hkWYvOU4azLHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}