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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f74b6da8a0f7981bdd8b96fb87996c5262065929e56fd61c7ef7755aedbaff' 
  AND token = '+r6RrmDgKHA6G3VgFj2Ov5A2B4/sWxuA5b9zB4sfyAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}