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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '761695546a3d9dfe1e49644eb5151c8ca6e79300974f21e60e4349035d61ee07' 
  AND token = 'NDnepRpO5DWh3YrhFS1JoM/TcV054q7P+5Xm8YWWqDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}