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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '171ec0c78c47d60c63befa001fa0c2136b439ce830ff05e576016b7cc9556fc2' 
  AND token = 'ioE3t5HlXcOc5fJstEBtuV7uR19r8hDuuHA8pZrG3vA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}