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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c36b3c09173d0a6535711353aaa7e114eb7f85bc7934b3d73a36e0aec67170a2' 
  AND token = 'WSi86sD9hghptdYvG/h1dwQkqFu9Zg2fG79nsHD0Wj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}