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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5104bae54d2a52c2f19aef9e7c861b4114bbcda9485e90f6c51773a2dcb6f557' 
  AND token = 'Sgi98YMh4dkAGz/LodwGJCL3AbKfJAueuD9BbHzxc4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}