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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd18728fa85efd66f6f7dafedb7471c763ce73715ae492d6a83c28e343727fd8' 
  AND token = 'Ir+UQBluDWfLp39An7yUj9hFc4mDjGC0Dap1q+zdngg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}