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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5acd58b2c3053d9116fe996db4fda89b706a324d59256b6868fd62348360609e' 
  AND token = 'QiDhCVp2rjG8XhSvTJN80839bDlEsHrgJ4eAjR19gRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}