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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd090cf43eaaeee07a41518d4697609fe600f30f964571d1e08d3e3e8ac1c2836' 
  AND token = 'WS6yzmHAjkrb9eQZI+8V1GKdvp3pFYLH/BIm8HqY3/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}