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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd007d8ef0f126b3f7e531c3b629db1c2b85f3384bded31c7576cc38ee4e33471' 
  AND token = 'TWyuIAVDPKPzHAWPlWFvs7iTmvzCPz+LoSpkcrmtQCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}