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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c6f614c5c62f2f9ccf49b711251f03edb946ebbf7a74ff2af15c889631051c8' 
  AND token = '/RodGHPzVZYeMLZaofo7encIamETNLyUD0jcpl8YscE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}