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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1df64113980445cf1467095eac0f736ed3e94a48de7867b41aad77fda8a34b8c' 
  AND token = 'Uk2NfLHX0eXnrzTRE10cs6vzlbUJ97cHh54ieDtFyEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}