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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96781f9896d1d58b233bb8f0e034a8389a9a7cc7f045b4059c2b565761d26d03' 
  AND token = 'oKBdSsTq3G+Ld0O3qxSOajD8doX2DiJhT+D0MXsBTPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}