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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb8bb800cd237dda81a4dd1c956e98c5ce7c7a4d88d6e5206242d991a1a6b035' 
  AND token = 'EgxfHeQyU+0XC00a28mqC6O4mRXWcL5pMRgP19lELns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}