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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bc5649c2c651cccb0146ad1a601c78471998b251989cb9278705b8efe22e49c' 
  AND token = '4TyfJRhmAq+g5ZtibY5xWz3KCHAyeciWseUNmgvcwR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}