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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ffa97eb3456dcc00e25f7c596ffe71578cc42b4a54501e8317a0283b87f3366' 
  AND token = 'c9ucMTNoDyxYhMIWFBLc+upRChTMMUt8vB7xYT16elo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}